Etanercept Inhibits B Cell Differentiation by Regulating TNFRII/TRAF2/NF-κB Signaling Pathway in Rheumatoid Arthritis

• Main Authors: Xiao-Yu Cai (Author), Yue Zhu (Author), Chen Wang (Author), Xiao-Yu Tang (Author), Le Han (Author), Jin-Ling Shu (Author), Xian-Zheng Zhang (Author), Fa-Qin Liang (Author), Jing-Ru Ge (Author), Li Xu (Author), Dan Mei (Author), Ling-Ling Zhang (Author), Wei Wei (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveTo explore the role of B cells in rheumatoid arthritis (RA) and the potential effects and mechanisms of etanercept on B cells.MethodsIn RA patients, the levels of tumor necrosis factor-α (TNF-α) and B cell activating factor (BAFF) were detected by ELISA. The percentage of B cell subsets was...