Polymorphisms in mTOR and Calcineurin Signaling Pathways Are Associated With Long-Term Clinical Outcomes in Kidney Transplant Recipients

• Autores principales: Antony Brayan Campos-Salazar (Autor), Fabiana Dalla Vecchia Genvigir (Autor), Claudia Rosso Felipe (Autor), Helio Tedesco-Silva (Autor), José Medina-Pestana (Autor), Gabriela Vieira Monteiro (Autor), Rodrigo de Gouveia Basso (Autor), Alvaro Cerda (Autor), Mario Hiroyuki Hirata (Autor), Rosario Dominguez Crespo Hirata (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Monitoring of immunosuppressive drugs, such as calcineurin and mTOR inhibitors, is essential to avoid undesirable kidney transplant outcomes. Polymorphisms in pharmacokinetics-related genes have been associated with variability in blood levels of immunosuppressive drugs and adverse effects, but infl...