Polymorphisms in mTOR and Calcineurin Signaling Pathways Are Associated With Long-Term Clinical Outcomes in Kidney Transplant Recipients

Polymorphisms in mTOR and Calcineurin Signaling Pathways Are Associated With Long-Term Clinical Outcomes in Kidney Transplant Recipients

Monitoring of immunosuppressive drugs, such as calcineurin and mTOR inhibitors, is essential to avoid undesirable kidney transplant outcomes. Polymorphisms in pharmacokinetics-related genes have been associated with variability in blood levels of immunosuppressive drugs and adverse effects, but infl...

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Main Authors: Antony Brayan Campos-Salazar (Author), Fabiana Dalla Vecchia Genvigir (Author), Claudia Rosso Felipe (Author), Helio Tedesco-Silva (Author), José Medina-Pestana (Author), Gabriela Vieira Monteiro (Author), Rodrigo de Gouveia Basso (Author), Alvaro Cerda (Author), Mario Hiroyuki Hirata (Author), Rosario Dominguez Crespo Hirata (Author)
Format: Book
Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
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