Increased IL17A, IFNG, and FOXP3 Transcripts in Moderate-Severe Psoriasis: A Major Influence Exerted by IL17A in Disease Severity

• Main Authors: Priscilla Stela Santana de Oliveira (Author), Michelly Cristiny Pereira (Author), Simão Kalebe Silva de Paula (Author), Emerson Vasconcelos Andrade Lima (Author), Mariana Modesto de Andrade Lima (Author), Rodrigo Gomes de Arruda (Author), Wagner Luís Mendes de Oliveira (Author), Ângela Luzia Branco Pinto Duarte (Author), Ivan da Rocha Pitta (Author), Moacyr Jesus Melo Barreto Rêgo (Author), Maira Galdino da Rocha Pitta (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Psoriasis is a chronic and recurrent dermatitis, mediated by keratinocytes and T cells. Several proinflammatory cytokines contribute to formation and maintenance of psoriatic plaque. The Th1/Th17 pathways and some of IL-1 family members were involved in psoriasis pathogenesis and could contribute to...