Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

• Main Authors: Elisabetta Muntoni (Author), Katia Martina (Author), Elisabetta Marini (Author), Marta Giorgis (Author), Loretta Lazzarato (Author), Iris Chiara Salaroglio (Author), Chiara Riganti (Author), Michele Lanotte (Author), Luigi Battaglia (Author)
• Format: Book
• Published: MDPI AG, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma is the most common and invasive primary tumor of the central nervous system and normally has a negative prognosis. Biodistribution in healthy animal models is an important preliminary study aimed at investigating the efficacy of chemotherapy, as it is mainly addressed towards residual c...