Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency
Serum and cellular proteins are targets for the formation of adducts with the β-lactam antibiotic amoxicillin. This process could be important for the development of adverse, and in particular, allergic reactions to this antibiotic. In studies exploring protein haptenation by amoxicillin, we observe...
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Main Authors: | María A. Pajares (Author), Tahl Zimmerman (Author), Francisco J. Sánchez-Gómez (Author), Adriana Ariza (Author), María J. Torres (Author), Miguel Blanca (Author), F. Javier Cañada (Author), María I. Montañez (Author), Dolores Pérez-Sala (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2020-03-01T00:00:00Z.
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