Efficacy and safety of biologics in the treatment of moderate to severe psoriasis: a comprehensive meta-analysis of randomized controlled trials

• Main Authors: Cassyano Januário Correr (Author), Inajara Rotta (Author), Thaís de Souza Teles (Author), Rangel Ray Godoy (Author), Bruno Salgado Riveros (Author), Mariana Martins Garcia (Author), Patrícia Rodrigues Gonçalves (Author), Michel Fleith Otuki (Author)
• Format: Book
• Published: Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We conducted a systematic review and metaanalysis of randomized placebo-controlled trials in moderate-to-severe psoriasis treated with biological agents, with a follow-up of 10-14 weeks. Overall, 41 studies, with mean Jadad score of 4.4, and 15,586 patients were included. For the efficacy outcomes P...