A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex

• Main Authors: Sewar Alkhashrom (Author), Jintawee Kicuntod (Author), Katharina Stillger (Author), Tamara Lützenburg (Author), Christian Anzenhofer (Author), Ines Neundorf (Author), Manfred Marschall (Author), Jutta Eichler (Author)
• Formato: Libro
• Publicado: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The replication of human cytomegalovirus (HCMV) involves a process termed nuclear egress, which enables translocation of newly formed viral capsids from the nucleus into the cytoplasm. The HCMV core nuclear egress complex (core NEC), a heterodimer of viral proteins pUL50 and pUL53, is therefore cons...