Arcyriaflavin a, a cyclin D1-cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis

• मुख्य लेखकों: Tomoko Hirakawa (लेखक), Kaei Nasu (लेखक), Yoko Aoyagi (लेखक), Kanetoshi Takebayashi (लेखक), Hisashi Narahara (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2017-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background We previously showed that microRNA-503 (miR-503) transfection into endometriotic cyst stromal cells (ECSCs) induced cell cycle arrest at the G0/G1 phase by suppressing cyclin D1. This finding prompted us to evaluate the potential therapeutic effects of cyclin D1 inhibitors in end...