The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2

• Main Authors: Lianzhong Zhao (Author), Xiaohan Zhang (Author), Zhu Wu (Author), Kun Huang (Author), Xiaomei Sun (Author), Huanchun Chen (Author), Meilin Jin (Author)
• Formato: Libro
• Publicado: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The influenza A virus poses serious public health challenges worldwide. Strikingly, small noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in antiviral responses, although the underlying mechanisms are essentially unknown. We now report that microRNA-340 (miR340) is do...