Is the anxiolytic-like effect of acute 8-0H-DPAT mediated by 5-HT<sub>1A</sub> receptors?
Para estudar o papel dos receptores 5-HT1A na ansiedade, realizamos uma curva dose-efeito com o agonista pleno de receptores 5HT1A administrado em ratos expostos ao labirinto em cruz elevado. A dose de 0,5mg/kg (IP) de 8-OH-DPAT aumentou significativamente a porcentagem de entradas e de tempo dispen...
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Main Authors: | Elisabeth Aparecida Audi (Author), Vagner Siqueira Alves (Author), Marcos Alberto Trombelli (Author), Alexandra Cândido de Barros (Author) |
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Format: | Book |
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Universidade Estadual de Maringá,
2008-07-01T00:00:00Z.
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