Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats

• المؤلفون الرئيسيون: Masatsugu Ohara (مؤلف), Shunsuke Ohnishi (مؤلف), Hidetaka Hosono (مؤلف), Koji Yamamoto (مؤلف), Kohei Yuyama (مؤلف), Hideki Nakamura (مؤلف), Qingjie Fu (مؤلف), Osamu Maehara (مؤلف), Goki Suda (مؤلف), Naoya Sakamoto (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2018-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Background. There are no approved drug treatments for liver fibrosis and nonalcoholic steatohepatitis (NASH), an advanced stage of fibrosis which has rapidly become a major cause of cirrhosis. Therefore, development of anti-inflammatory and antifibrotic therapies is desired. Mesenchymal stem cell- (...