YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice

• المؤلفون الرئيسيون: Zhan Jing-Lun (مؤلف), Chai Shuang (مؤلف), Zhao Li-Mei (مؤلف), Liu Xiao-Dong (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Background: The inflammatory factor YKL-40 is associated with various inflammatory diseases and is key to remodeling inflammatory cells and tissues. YKL-40 (Chi3l1) promotes the activation of tissue factor (TF), leading to intrahepatic vascular coagulation (IAOC) and liver injury. TF is a key promot...