Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome

• Main Authors: Beverly A. Karpinski (Author), Thomas M. Maynard (Author), Matthew S. Fralish (Author), Samer Nuwayhid (Author), Irene E. Zohn (Author), Sally A. Moody (Author), Anthony-S. LaMantia (Author)
• Format: Book
• Published: The Company of Biologists, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We assessed feeding-related developmental anomalies in the LgDel mouse model of chromosome 22q11 deletion syndrome (22q11DS), a common developmental disorder that frequently includes perinatal dysphagia - debilitating feeding, swallowing and nutrition difficulties from birth onward - within its phen...