Design and fabrication of r-hirudin loaded dissolving microneedle patch for minimally invasive and long-term treatment of thromboembolic disease
Cardiovascular disease is the leading cause of global mortality, with anticoagulant therapy being the main prevention and treatment strategy. Recombinant hirudin (r-hirudin) is a direct thrombin inhibitor that can potentially prevent thrombosis via subcutaneous (SC) and intravenous (IV) administrati...
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Main Authors: | Mengfang Wu (Author), Tian Xia (Author), Yaran Li (Author), Tianfa Wang (Author), Shijia Yang (Author), Jinchao Yu (Author), Qiaoyan Liang (Author), Teng Shen (Author), Min Yu (Author), Bing Zhao (Author) |
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Format: | Book |
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Elsevier,
2022-03-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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