Exploring Pyrrolo-Fused Heterocycles as Promising Anticancer Agents: An Integrated Synthetic, Biological, and Computational Approach

Exploring Pyrrolo-Fused Heterocycles as Promising Anticancer Agents: An Integrated Synthetic, Biological, and Computational Approach

Five new series of pyrrolo-fused heterocycles were designed through a scaffold hybridization strategy as analogs of the well-known microtubule inhibitor phenstatin. Compounds were synthesized using the 1,3-dipolar cycloaddition of cycloimmonium N-ylides to ethyl propiolate as a key step. Selected co...

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Main Authors: Roxana-Maria Amărandi (Author), Maria-Crist (Author), Lăcrămioara Popovici (Author), Catalina Ionica Ciobanu (Author), Andrei Neamțu (Author), Ionel I. Mangalagiu (Author), Ramona Danac (Author)
Format: Book
Published: MDPI AG, 2023-06-01T00:00:00Z.
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3rd Floor Main Library

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