High frequency of Machado-Joseph disease identified in Southeastern Chinese kindreds with spinocerebellar ataxia

• Main Authors: Gan Shi-Rui (Author), Shi Sheng-Sheng (Author), Wu Jian-Jun (Author), Wang Ning (Author), Zhao Gui-Xian (Author), Weng Sheng-Tong (Author), Murong Shen-Xing (Author), Lu Chuan-Zhen (Author), Wu Zhi-Ying (Author)
• Format: Book
• Published: BMC, 2010-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Machado-Joseph disease (MJD), caused by a CAG repeat expansion located in exon10 of the <it>ATXN3 </it>gene, is now regarded as one of the most common spinocerebellar ataxia (SCA) in the world. The relative frequency of M...