Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels

• Những tác giả chính: Fenling Fan (Tác giả), Yifan Zou (Tác giả), Yousen Wang (Tác giả), Peng Zhang (Tác giả), Xiaoyu Wang (Tác giả), Anthony M. Dart (Tác giả), Yuliang Zou (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background: Similarities in the biology of pulmonary hypertension and cancer suggest that anticancer therapies, such as sanguinarine, may also be effective in treating pulmonary hypertension. This, along with underlying biochemical pathways, is investigated in this study.Methods: Rats were subjected...