A novel form of docetaxel polymeric micelles demonstrates anti-tumor and ascites-inhibitory activities in animal models as monotherapy or in combination with anti-angiogenic agents

• Main Authors: Leilei Guo (Author), Xiaokang Qin (Author), Liting Xue (Author), Janine Y. Yang (Author), Yumei Zhang (Author), Shunwei Zhu (Author), Gang Ye (Author), Renhong Tang (Author), WenQing Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Malignant ascites (MA) is caused by intraperitoneal spread of solid tumor cells and results in a poor quality of life. Chemotherapy is a common first-line treatment for patients with MA. Taxotere ® (DTX) is widely used in solid tumor therapies. However, the low water solubility and side effects caus...