Sensitive spectrophotometric assay of simvastatin in pharmaceuticals using permanganate

• Auteurs principaux: Kalsang Tharpa (Auteur), Kanakapura Basavaiah (Auteur), Nagaraju Rajedraprasad (Auteur), Kanakapura Basavaiah Vinay (Auteur), Salmara Ganeshbhat Hiriyanna (Auteur)
• Format: Livre
• Publié: Universidade de São Paulo, 2010-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Two simple, sensitive, selective and inexpensive spectrophotometric methods are described for the determination of simvastatin (SMT) in bulk drug and in tablets using permanganate as the oxidimetric reagent. In method A, SMT is treated with a measured excess of permanganate in acetic acid medium and...