Thymoquinone-Enriched Naringenin-Loaded Nanostructured Lipid Carrier for Brain Delivery via Nasal Route: In Vitro Prospect and In Vivo Therapeutic Efficacy for the Treatment of Depression

• Main Authors: Farheen Fatima Qizilbash (Author), Muhammad Usama Ashhar (Author), Ameeduzzafar Zafar (Author), Zufika Qamar (Author), Annu (Author), Javed Ali (Author), Sanjula Baboota (Author), Mohammed M. Ghoneim (Author), Sultan Alshehri (Author), Asgar Ali (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured lipid carrier (NLC) was developed and delivered via the nasal route for depression. Thymoquinone (TQ) oil was used as the liquid lipid and provided synergistic effects. A TQ- and NGN-enriched NLC was developed vi...