Thymoquinone-Enriched Naringenin-Loaded Nanostructured Lipid Carrier for Brain Delivery via Nasal Route: In Vitro Prospect and In Vivo Therapeutic Efficacy for the Treatment of Depression

• Hauptverfasser: Farheen Fatima Qizilbash (Verfasst von), Muhammad Usama Ashhar (Verfasst von), Ameeduzzafar Zafar (Verfasst von), Zufika Qamar (Verfasst von), Annu (Verfasst von), Javed Ali (Verfasst von), Sanjula Baboota (Verfasst von), Mohammed M. Ghoneim (Verfasst von), Sultan Alshehri (Verfasst von), Asgar Ali (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured lipid carrier (NLC) was developed and delivered via the nasal route for depression. Thymoquinone (TQ) oil was used as the liquid lipid and provided synergistic effects. A TQ- and NGN-enriched NLC was developed vi...