Anti-inflammatory effect of gallic acid on HaCaT keratinocytes through the inhibition of MAPK-, NF-kB-, and Akt-dependent signaling pathways

• Main Authors: Polly Ho-Ting Shiu (Author), Chengwen Zheng (Author), Panthakarn Rangsinth (Author), Wen Wang (Author), Jingjing Li (Author), Renkai Li (Author), George Pak-Heng Leung (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objectives of the present study were to evaluate the antioxidant and anti-inflammatory effects of gallic acid, a naturally occurring triphenolic compound, on HaCaT keratinocytes and study its mechanisms of action. The results showed that gallic acid at concentrations lower than 30 µM was non-tox...