Pharmacokinetics of propafenone hydrochloride sustained-release capsules in male beagle dogs

• Main Authors: Liping Pan (Author), Yafang Qian (Author), Minlu Cheng (Author), Pan Gu (Author), Yanna He (Author), Xiaowen Xu (Author), Li Ding (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This paper describes the development and validation of a liquid chromatography-mass spectrometric assay for propafenone and its application to a pharmacokinetic study of propafenone administered as a new propafenone hydrochloride sustained-release capsule (SR-test), as an instant-release tablet (IR-...