Skeletal muscle mass loss and dose‐limiting toxicities in metastatic colorectal cancer patients

• Main Authors: Sophie Kurk (Author), Petra Peeters (Author), Rebecca Stellato (Author), B. Dorresteijn (Author), Pim deJong (Author), Marion Jourdan (Author), Geert‐Jan Creemers (Author), Frans Erdkamp (Author), Felix deJongh (Author), Peter Kint (Author), Lieke Simkens (Author), Bea Tanis (Author), Manuel Tjin‐A‐Ton (Author), Ankie Van Der Velden (Author), Cornelis Punt (Author), Miriam Koopman (Author), Anne May (Author)
• Format: Book
• Published: Wiley, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Increasing evidence suggests that severe skeletal muscle index (SMI) loss (sarcopenia) is associated with poor overall survival in metastatic colorectal cancer patients, but its mechanisms are unknown. We recently found, using data of the randomized phase 3 CAIRO3 study, that SMI...