Loop-Mediated Isothermal Amplification for Laboratory Confirmation of Buruli Ulcer Disease-Towards a Point-of-Care Test.

• Main Authors: Marcus Beissner (Author), Richard Odame Phillips (Author), Florian Battke (Author), Malkin Bauer (Author), Kossi Badziklou (Author), Fred Stephen Sarfo (Author), Issaka Maman (Author), Agata Rhomberg (Author), Ebekalisai Piten (Author), Michael Frimpong (Author), Kristina Lydia Huber (Author), Dominik Symank (Author), Moritz Jansson (Author), Franz Xaver Wiedemann (Author), Abiba Banla Kere (Author), Karl-Heinz Herbinger (Author), Thomas Löscher (Author), Gisela Bretzel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:As the major burden of Buruli ulcer disease (BUD) occurs in remote rural areas, development of point-of-care (POC) tests is considered a research priority to bring diagnostic services closer to the patients. Loop-mediated isothermal amplification (LAMP), a simple, robust and cost-effectiv...