Cancer cell reprogramming to identify the genes competent for generating liver cancer stem cells

• Main Authors: Kenly Wuputra (Author), Chang-Shen Lin (Author), Ming-Ho Tsai (Author), Chia-Chen Ku (Author), Wen-Hsin Lin (Author), Ya-Han Yang (Author), Kung-Kai Kuo (Author), Kazunari K. Yokoyama (Author)
• Format: Book
• Published: BMC, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The cancer stem cell (CSC) hypothesis postulates that cancer originates from the malignant transformation of stem/progenitor cells and is considered to apply to many cancers, including liver cancer. Identification that CSCs are responsible for drug resistance, metastasis, and secondary tumo...