Innovative Nanoparticles Enhance N-Palmitoylethanolamide Intraocular Delivery

• Main Authors: Carmelo Puglia (Author), Paolo Blasi (Author), Carmine Ostacolo (Author), Eduardo Sommella (Author), Claudio Bucolo (Author), Chiara B. M. Platania (Author), Giovanni L. Romano (Author), Federica Geraci (Author), Filippo Drago (Author), Debora Santonocito (Author), Barbara Albertini (Author), Pietro Campiglia (Author), Giovanni Puglisi (Author), Rosario Pignatello (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanostructured lipid carriers (NLCs) loaded with palmitoylethanolamide (PEA) were formulated with the aim to enhance ocular bioavailability of PEA, particularly to the back of the eye. Technological characterization (e.g., size, charge) of NLC loaded with PEA formulation (PEA-NLC) was performed, and...