Immunohistochemical profile of HIF-1α, VEGF-A, VEGFR2 and MMP9 proteins in tegumentary leishmaniasis Estudo da expressão imunohistoquímica das proteínas HIF-1α, VEGF-A, VEGFR2 e MMP9 em leishmaniose tegumentar americana

• Main Authors: Carlos Alberto de Carvalho Fraga (Author), Marcos Vinicius Macedo de Oliveira (Author), Lucas Rodrigues Alves (Author), Agostinho Gonçalves Viana (Author), Adriana Alkmin de Sousa (Author), Sílvio Fernando Guimarães Carvalho (Author), Alfredo Maurício Batista De Paula (Author), Ana Cristina de Carvalho Botelho (Author), André Luiz Sena Guimarães (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia, 2012-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Leishmaniasis is one of the most important infectious diseases worldwide. Our study can provide more knowledge about angiogenic and hypoxic events in leishmaniasis. We attempted to verify whether the HIF-1 α protein expression may be associated to VEGF-A, VEGFR2 and MMP9 in leishmanial l...