Novel benzamido derivatives as PTP1B inhibitors with anti-hyperglycemic and lipid-lowering efficacy
Based on a non-competitive and selective PTP1B inhibitor reported by us previously, thirty-nine benzamido derivatives were designed and synthesized as novel PTP1B inhibitors. Among them, twelve compounds exhibited IC50 values at micromolar level against human recombinant PTP1B, and most of them exhi...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2018-10-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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