Molecular action of pyriproxyfen: Role of the Methoprene-tolerant protein in the pyriproxyfen-induced sterilization of adult female mosquitoes.

• Main Authors: Tahmina Hossain Ahmed (Author), T Randolph Saunders (Author), Donald Mullins (Author), Mohammad Zillur Rahman (Author), Jinsong Zhu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exposure of adult mosquitoes to pyriproxyfen (PPF), an analog of insect juvenile hormone (JH), has shown promise to effectively sterilize female mosquitoes. However, the underlying mechanisms of the PPF-induced decrease in mosquito fecundity are largely unknown. We performed a comprehensive study to...