TNF-α Deficiency Prevents Renal Inflammation and Oxidative Stress in Obese Mice

• Main Authors: Huaiguo Wang (Author), Jian Li (Author), Zhibo Gai (Author), Gerd A. Kullak-Ublick (Author), Zewei Liu (Author)
• Formato: Libro
• Publicado: Karger Publishers, 2017-07-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Background/Aims: Obese patients and experimental animals exhibit high levels of inflammatory cytokines, such as tumor necrosis factor (TNF)-α. However, the role of TNF-α in the pathophysiologic process in obesity induced kidney damage is still unknown. Methods: We used TNF-α deficient mice and wild-...