Antibody-drug conjugates: beyond current approvals and potential future strategies

• Main Authors: Siddharth Menon (Author), Sagun Parakh (Author), Andrew M. Scott (Author), Hui K. Gan (Author)
• 格式: 圖書
• 出版: Open Exploration Publishing Inc., 2022-04-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The recent approvals for antibody-drug conjugates (ADCs) in multiple malignancies in recent years have fuelled the ongoing development of this class of drugs. These novel agents combine the benefits of high specific targeting of oncogenic cell surface antigens with the additional cell kill from high...