PTPN22 Silencing in Human Acute T-Cell Leukemia Cell Line (Jurkat Cell) and its Effect on the Expression of miR-181a and miR-181b

• Main Authors: Elham Baghbani (Author), Vahid Khaze (Author), Sanam Sadreddini (Author), Ahad Mokhtarzadeh (Author), Behzad Mansoori (Author), Ali Mohammadi (Author), Vida Vatankhahan (Author), Parisa Toosi (Author), Behzad Baradaran (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: T-cell acute lymphoblastic leukemia (T-ALL) is one of the most common malignancies associated with T-lymphocytes, accounting for 10 to 15 percent of ALL cases in children and 25 percent in adults. Innovative therapeutic approaches that overcome ineffective treatments on tumor cells may be a...