Dysregulated arginine metabolism in precursor B-cell acute lymphoblastic leukemia in children: a metabolomic study

• Main Authors: Wenqing Wang (Author), Liuting Yu (Author), Zhen Li (Author), Yan Xiao (Author), Hao Jiang (Author), Yan-lai Tang (Author), Yun Chen (Author), Hongman Xue (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Precursor B-cell acute lymphoblastic leukemia (B-ALL) is the most common cancers in children. Failure of induction chemotherapy is a major factor leading to relapse and death in children with B-ALL. Given the importance of altered metabolites in the carcinogenesis of pediatric B-...