Tamoxifen Twists Again: On and Off-Targets in Macrophages and Infections

• Main Authors: Chiara Sfogliarini (Author), Giovanna Pepe (Author), Arianna Dolce (Author), Sara Della Torre (Author), Maria Candida Cesta (Author), Marcello Allegretti (Author), Massimo Locati (Author), Elisabetta Vegeto (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Beyond the wide use of tamoxifen in breast cancer chemotherapy due to its estrogen receptor antagonist activity, this drug is being assayed in repurposing strategies against a number of microbial infections. We conducted a literature search on the evidence related with tamoxifen activity in macropha...