Negligible Effect of Quercetin in the Pharmacokinetics of Sulfasalazine in Rats and Beagles: Metabolic Inactivation of the Interaction Potential of Quercetin with BCRP

Breast cancer resistance protein (BCRP) mediates pharmacokinetic drug interactions. This study evaluated the potential of quercetin to inhibit and induce BCRP in vitro and in vivo. The inhibition of BCRP was investigated for quercetin and its metabolites using BCRP/mBcrp1-overexpressing MDCKII cells...

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Bibliographic Details
Main Authors: Ju-Hee Oh (Author), Dokeun Kim (Author), Haejun Lee (Author), Gyeonghee Kim (Author), Taehoon Park (Author), Min Chang Kim (Author), Young-Joo Lee (Author)
Format: Book
Published: MDPI AG, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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