Development and Characterization of a Semi-Solid Dosage Form of Meglumine Antimoniate for Topical Treatment of Cutaneous Leishmaniasis

• Main Authors: Diana Berenguer (Author), Lilian Sosa (Author), Magdalena Alcover (Author), Marcella Sessa (Author), Lyda Halbaut (Author), Carme Guillén (Author), Roser Fisa (Author), Ana Cristina Calpena-Campmany (Author), Cristina Riera (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cutaneous leishmaniasis (CL) is treated with painful intralesional injections of meglumine antimoniate (MA). With the aim of developing an alternative topical treatment for CL, a gel-based formulation with 30% MA was prepared and its physicochemical properties, stability and rheological behavior wer...