Adipocyte-Specific Expression of PGC1α Promotes Adipocyte Browning and Alleviates Obesity-Induced Metabolic Dysfunction in an HO-1-Dependent Fashion

• Main Authors: Shin-Hsueh Shen (Author), Shailendra P. Singh (Author), Marco Raffaele (Author), Maayan Waldman (Author), Edith Hochhauser (Author), Juancarlos Ospino (Author), Michael Arad (Author), Stephen J. Peterson (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies suggest that PGC1-α plays a crucial role in mitochondrial and vascular function, yet the physiological significance of PGC1α and HO expression in adipose tissues in the context of obesity-linked vascular dysfunction remains unclear. We studied three groups of six-week-old C57BL/6J mal...