Synthesis of silymarin−selenium nanoparticle conjugate and examination of its biological activity in vitro

• Главные авторы: Sergey Staroverov (Автор), Sergey Kozlov (Автор), Alexander Fomin (Автор), Konstantin Gabalov (Автор), Vitaliy Khanadeev (Автор), Dmitry Soldatov (Автор), Ivan Domnitsky (Автор), Lev Dykman (Автор), Sergey V. Akchurin (Автор), Olga Guliy (Автор)
• Формат: ‌
• Опубликовано: International Association of Physical Chemists (IAPC), 2021-11-01T00:00:00Z.
• Предметы: article
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Silymarin (Sil) was conjugated to selenium nanoparticles (SeNPs) to increase Sil bioavailability. The conjugates were monodisperse; the average diameter of the native SeNPs was ~ 20-50 ± 1.5 nm, whereas that of the conjugates was 30-50 ± 0.5 nm. The use of SeNPs to increase the bioavailability of Sy...