Overview of Histone Deacetylase Inhibitors in Haematological Malignancies

• Asıl Yazarlar: H. Miles Prince (Yazar), Simon Harrison (Yazar), Mark J. Bishton (Yazar), Ricky W. Johnstone (Yazar), Michael Dickinson (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2010-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Histone deacetylase inhibitors (HDACi) can induce hyperacetylation of both histone and non-histone target resulting in epigenetic reprogramming and altered activity, stability and localisation of non-histone proteins to ultimately mediate diverse biological effects on cancer cells and their microenv...