Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

• المؤلفون الرئيسيون: Xinghui Han (مؤلف), Yuanyuan He (مؤلف), Gulan Zeng (مؤلف), Yonghong Wang (مؤلف), Wen Sun (مؤلف), Junchao Liu (مؤلف), Yanyan Sun (مؤلف), Jian Yu (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2017-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...