Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

• Hauptverfasser: Xinghui Han (Verfasst von), Yuanyuan He (Verfasst von), Gulan Zeng (Verfasst von), Yonghong Wang (Verfasst von), Wen Sun (Verfasst von), Junchao Liu (Verfasst von), Yanyan Sun (Verfasst von), Jian Yu (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2017-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...