Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

• Autores principales: Xinghui Han (Autor), Yuanyuan He (Autor), Gulan Zeng (Autor), Yonghong Wang (Autor), Wen Sun (Autor), Junchao Liu (Autor), Yanyan Sun (Autor), Jian Yu (Autor)
• Formato: Libro
• Publicado: BMC, 2017-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...