Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

• Auteurs principaux: Xinghui Han (Auteur), Yuanyuan He (Auteur), Gulan Zeng (Auteur), Yonghong Wang (Auteur), Wen Sun (Auteur), Junchao Liu (Auteur), Yanyan Sun (Auteur), Jian Yu (Auteur)
• Format: Livre
• Publié: BMC, 2017-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...