Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats
Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...
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