Carfilzomib-Induced Thrombotic Microangiopathy Treated with Eculizumab: A Case Report and Rapid Literature Review

• Main Authors: Federica Pallotti (Author), Claire Queffeulou (Author), Mathieu Bellal (Author), Bastien Jean-Jacques (Author), Anne-Claire Gac (Author), Valérie Chatelet (Author), Annabel Boyer (Author), Victor Gueutin (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Thrombotic microangiopathies (TMAs) can be induced by drugs. Recent works have indicated proteasome inhibitors, including carfilzomib, as a possible new causative agent. Although the physiopathology and management of carfilzomib-induced TMA are still unknown, eculizumab seems to be effic...