Tolmetin Sodium Fast Dissolving Tablets for Rheumatoid Arthritis Treatment: Preparation and Optimization Using Box-Behnken Design and Response Surface Methodology

• Main Authors: Mahmoud M. A. Elsayed (Author), Moustafa O. Aboelez (Author), Bakheet E. M. Elsadek (Author), Hatem A. Sarhan (Author), Khaled Ali Khaled (Author), Amany Belal (Author), Ahmed Khames (Author), Yasser A. Hassan (Author), Amany A. Abdel-Rheem (Author), Eslam B. Elkaeed (Author), Mohamed Raafat (Author), Mahmoud Elkot Mostafa Elsadek (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tolmetin sodium (TLM) is a non-steroidal anti-inflammatory drug (NSAIDs). TLM is used to treat inflammation, skeletal muscle injuries, and discomfort associated with bone disorders. Because of the delayed absorption from the gastro intestinal tract (GIT), the currently available TLM dosage forms hav...