Evaluation of the Predictive Performance of Population Pharmacokinetic Models of Adalimumab in Patients with Inflammatory Bowel Disease

• Main Authors: Silvia Marquez-Megias (Author), Amelia Ramon-Lopez (Author), Patricio Más-Serrano (Author), Marcos Diaz-Gonzalez (Author), Maria Remedios Candela-Boix (Author), Ricardo Nalda-Molina (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adalimumab is a monoclonal antibody used for inflammatory bowel disease. Due to its considerably variable pharmacokinetics, the loss of response and the development of anti-antibodies, it is highly recommended to use a model-informed precision dosing approach. The aim of this study is to evaluate th...