Liquid-liquid extraction combined with high performance liquid chromatography-diode array-ultra-violet for simultaneous determination of antineoplastic drugs in plasma

• Main Authors: Ananda Lima Sanson (Author), Suéllen Cristina Rennó Silva (Author), Matheus Coutinho Gonçalves Martins (Author), Alexandre Giusti-Paiva (Author), Patrícia Penido Maia (Author), Isarita Martins (Author)
• Format: Book
• Published: Universidade de São Paulo, 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A liquid-liquid extraction (LLE) combined with high-performance liquid chromatography-diode array detection method for simultaneous analysis of four chemically and structurally different antineoplastic drugs (cyclophosphamide, doxorubicin, 5-fluorouracil and ifosfamide) was developed. The assay was...