Dimethyl Fumarate Strongly Ameliorates Gray and White Matter Brain Injury and Modulates Glial Activation after Severe Hypoxia-Ischemia in Neonatal Rats

• Главные авторы: Jon Ander Alart (Автор), Antonia Álvarez (Автор), Ana Catalan (Автор), Borja Herrero de la Parte (Автор), Daniel Alonso-Alconada (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2024-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Neonatal hypoxia-ischemia is a major cause of infant death and disability. The only clinically accepted treatment is therapeutic hypothermia; however, cooling is less effective in the most severely encephalopathic infants. Here, we wanted to test the neuroprotective effect of the antioxidant dimethy...