Advancements in therapeutically-targeting orphan GPCRs
G-protein coupled receptors (GPCRs) are popular biological targets for drug discovery and development. To date there are more than 140 orphan GPCRs, i.e. receptors whose endogenous ligands are unknown. Traditionally orphan GPCRs have been difficult to study and the development of therapeutic compoun...
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Frontiers Media S.A.,
2015-05-01T00:00:00Z.
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